CAS 6293-83-0 2-Iodo-4-nitroaniline-Professional supplier

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Specification of 2-Iodo-4-nitroaniline

Item Specifications
Appearance Yellow crystalline powder
Purity (HPLC) ≥97.0%/≥98.0%
Melting Point 105-109°C
Loss on Drying ≤0.30%

 

Basic information of 2-Iodo-4-nitroaniline

CAS:6293-83-0

Standard:Technical grade

Model:SC-001

Production Capacity:50MT/month

Certificate: ISO, COA, MSDS

Loading port: Shanghai

Synonyms:2-Iodo-4-nitrobenzenamine, 4-Amino-3-iodonitrobenzene
MF:C6H5IN2O2

Usage of 2-Iodo-4-nitroaniline
Multifunctional Aromatic Coupling Building Block

Triple-reactive substituted aniline containing iodo, amino and nitro functional groups. The aryl iodide group serves as excellent reaction site for palladium-catalyzed Suzuki, Buchwald and Sonogashira cross-coupling reactions to construct complex biaryl and heterocyclic skeletons, widely used in multi-step fine organic synthesis routes for lab research and pilot-scale production.

2.Pharmaceutical Intermediate for Small-Molecule Drug Synthesis

Key precursor for manufacturing kinase inhibitors, anti-inflammatory and anti-infective APIs. The nitro group can be reduced to second amino group to produce 2-iodo-p-phenylenediamine, a core raw material for targeted oral therapeutic agents and heterocyclic drug fragments. Its unique iodine substitution improves molecular binding affinity with biological target proteins in medicinal chemistry screening programs.

3.Dye & Pigment Synthetic Raw Material

Vital starting material for manufacturing azo dyes, disperse textile colorants and organic fluorescent probes. The amino group enables diazotization coupling reactions to form long-stable chromogenic structures; iodine substituent enhances light fastness and thermal stability of finished dyes for textile printing and ink production.

4.Laboratory Research Analytical Reagent

Standard aromatic iodine reagent for organic chemistry laboratory teaching and research. Adopted to explore selective functional group transformation, redox reactions and aromatic ring derivatization experiments; also used as substrate for developing chromatographic stationary phase modifiers and biochemical labeling probes.

Package of 2-Iodo-4-nitroaniline

25kg/drum or according to the customers’ demand

Storage of 2-Iodo-4-nitroaniline

Stored in the dry and ventilated inside storeroom, prevent direct sunlight, slightly pile and put down.

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