CAS 180516-87-4 4-Carboxylphenylboronic acid pinacol ester-Professional supplier
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We can supply 4-Carboxylphenylboronic acid pinacol ester (CAS:180516-87-4) with stable quality and bulk stock.
Specification of 4-Carboxylphenylboronic acid pinacol ester
| Item | Specifications |
| Appearance | White crystalline powder |
| Purity (HPLC) | ≥98.0% |
| Melting Point | 228-231°C |
Basic information of 4-Carboxylphenylboronic acid pinacol ester
CAS:180516-87-4
Standard:Technical grade
Model:SC-001
Production Capacity:50MT/month
Certificate: ISO, COA, MSDS
Loading port: Shanghai
Synonyms:4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)benzoic acid, 2-(4-Carboxyphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane, 4-Carboxyphenylboronic acid pinacolate
MF:C13H17BO4
Usage of 4-Carboxylphenylboronic acid pinacol ester
1.Suzuki-Miyaura Cross-Coupling Reaction Intermediate
Dual-functional aryl boronate building block equipped with both boronate pinacol ester and carboxyl reactive groups. It serves as a core coupling reagent for palladium-catalyzed Suzuki cross-coupling reactions, widely used for constructing complex biaryl skeletons in fine organic synthesis. The pinacol boronate structure offers superior air and moisture stability compared to raw boronic acid, convenient for long-term storage and industrial scale-up synthesis.
2.Pharmaceutical API & Drug Intermediate
Key synthetic precursor for small-molecule therapeutic agents, kinase inhibitors, anti-inflammatory and anti-tumor drug candidates. The terminal carboxylic acid group enables amide condensation, esterification and other derivatization reactions to introduce bioactive fragments. It is extensively adopted in synthetic routes for targeted oral medicines and biopharmaceutical intermediates in medicinal chemistry labs.
3.Optical Material & Polymer Functional Monomer
Special boron-containing monomer for preparing fluorescent polymers, organic luminescent materials and sensor probes. The carboxyl group supports covalent grafting onto epoxy, polyamide and rubber materials; used as crosslinking modifier for epoxidized natural rubber to enhance bonding performance between polymer matrix and inorganic silica filler.
4.Laboratory Research Biochemical Reagent
Standard organic boronic reagent for life science and analytical chemistry research. Applied in the synthesis of glucose fluorescent detection probes, biological molecular labeling reagents and chromatographic stationary phase modifiers for carbohydrate separation experiments.
Package of 4-Carboxylphenylboronic acid pinacol ester
25kg/drum or according to the customers’ demand
Storage of 4-Carboxylphenylboronic acid pinacol ester
Stored in the dry and ventilated inside storeroom, prevent direct sunlight, slightly pile and put down.
